Why Does GRAPEFRUIT Turn One STATIN Into Several?
Chapters
About this video
Why does grapefruit juice turn a single statin dose into several? The answer lies in intestinal CYP3A4 and furanocoumarins, a discovery that began with a 1989 accident. Learn how this interaction works and why it matters for your medication. Chapters: 00:00 One Glass, Several Doses 00:11 Two Questions 00:23 Not All Statins 00:35 1989 00:46 A Taste Problem 00:58 The Numbers Were Wrong 01:10 Testing It Himself 01:22 Tripled 01:32 Follow the Pill 01:43 The Wall 01:54 CYP3A4 02:06 Most Never Arrive 02:17 The Label Assumes 02:29 Furanocoumarins 02:40 Not Blocked. Destroyed. 03:01 Permanent 03:12 Gates Down 03:32 Skip the Gut, Skip the Problem 03:43 Everyone Starts Different 03:55 Unguarded 04:05 The Fraction Climbs 04:15 Many Times Higher 04:25 Same Pill, Different Body 04:45 Recovery vs Ruin 04:55 Built From Scratch 05:06 Days, Not Hours 05:26 Why Only Some 05:46 Moderate 06:06 Not Inconsistency 06:17 Muscle, Not Just Liver 06:28 Fibres Fray 06:39 Rhabdomyolysis 06:51 Why It's On the Label 07:11 Same Road 07:22 Same Family 07:41 A Negotiation 07:53 Not Stronger — Unguarded 08:04 Ask a Pharmacist 08:16 Still Printed Today
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