Why Does Grapefruit Turn One Statin Into Several? CYP3A4 and Furanocoumarins Explained
About this video
Why does grapefruit turn one statin into several? In this video, we explain how furanocoumarins in grapefruit permanently inhibit intestinal CYP3A4, causing a single dose of a statin to act like multiple doses. You'll learn the mechanism, the 1989 accident that led to the discovery, and why the effect is not blocked but destroyed. Chapters: 00:00 WHY DOES GRAPEFRUIT TURN ONE STATIN 00:14 Not Blocked. Destroyed. 00:35 Permanent
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