Why Grapefruit Turns One Statin Into Several: CYP3A4, Furanocoumarins, and the 1989 Discovery

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Why does grapefruit turn one statin into several? In this video, we explain how intestinal CYP3A4 and furanocoumarins in grapefruit cause a single dose of a statin to act like multiple doses, and how a 1989 accident put a fruit on a drug label. You'll learn the mechanism behind this dangerous interaction and why it's not just a timing problem. Chapters: 00:00 WHY DOES GRAPEFRUIT TURN ONE STATIN 00:13 Recovery vs Ruin 00:24 Built From Scratch 00:34 Days, Not Hours

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Why Grapefruit Turns One Statin Into Several: CYP3A4, Furanocoumarins, and the 1989 Discovery